The ErbB family of RTKs, which consist of Epidermal growth factor receptor (EGFR) (ErbB1 or HER1), ErbB2 (HER2 or Neu), ErbB3 (HER3), and ErbB4 (HER4), have been shown to promote tumor progression in various cancer types [7]. The gene discussed is ERBB2; the disease is cancer.