TANGO2 and neoplasm: OR5H14 is an olfactory receptor and while another olfactory receptor has been shown to promote PCa tumor development [20, 21], nothing is known about the function of OR5H14. The risk-associated variant in TANGO2 is a stop-gain variant predicted to result in early truncation of multiple TANGO2 isoforms, including several expressed in the prostate (http://www.gtexportal.org/).