An Oncomine database analysis also demonstrated that VEGF-C expression was positively correlated with the expression of some CSC markers, such as OCT4, KLF4, NANOG, CD44, CD34 and CD133 (Supplementary Figure S1a-S1f), suggesting that VEGF-C increases the CSC features of skin cancer cells. This evidence concerns the gene KLF4 and skin neoplasm.