VEGFC and skin cancer: To further investigate whether VEGF-C affects skin cancer cell migration and invasion abilities, we established stable VEGF-C-knockdown cells (BCC/shVEGF-C and A2058/shVEGF-C) and control cells (BCC/shCtrl and A2058/shCtrl), and VEGF-C mRNA expression was measured by qRT-PCR analysis (Figure 1b).