In subcutaneous implantation models, shRNA-mediated reduction in HOXB7 expression in the BGC-823 cell line caused significant reduction tumor growth relative to controls (1301.38 ± 294.25 mm3 in BGC-823-shNC group vs. 255.79 ± 72.35 mm3 in BGC-823-shB7 group, Figure 3A–3B; t-test, P<0.05). Here, HOXB7 is linked to neoplasm.