To evaluate the possible role of HOXB7 in the tumorigenesis and invasiveness of human GC cells, we generated a HOXB7 shRNA knockdown GC cell line BGC-823-shB7, and a HOXB7 overexpression GC cell line, MGC-803-B7 (Figure 2A). The gene discussed is HOXB7; the disease is gastric cancer.