SAT1 and colorectal carcinoma: In order to investigate whether inhibition of GSK3β activity could restore SSAT-induced cell growth and invasion progress in hepatocellular and colorectal carcinoma cells, we then performed the MTT cell viability assay and Boyden chamber transwell assay in the absence or presence of LiCl in SMMC7721, HepG2 and HCT116 cells transfected with SSAT.