TMED3 and hepatocellular carcinoma: To investigate the clinical significance of TMED3 in HCC, the cohort of 313 HCC patients was divided into two groups according to the tumor IHC score: a high TMED3 expression group (tumor score > 2, n = 187) and a low TMED3 expression group (tumor score ≤ 2, n = 126).