A univariate analysis indicated that among the clinicopathological characteristics, TMED3 expression level, tumor size, vascular invasion, and positivity for AFP, HBsAg, or HBeAg were correlated with RFS, and TMED3 expression level, tumor size, tumor number, AFP positivity, vascular invasion, presence of HBsAg, and presence of HBeAg were correlated with OS (Table 2). Here, AFP is linked to neoplasm.