A strong genetic link exists between schizophrenia and VPAC2 receptors: two recent publications from independent groups found that schizophrenia was associated with the presence of an increased number of the gene copies encoding the VPAC2 receptor, caused by duplications of the 7q36.3 chromosomal region VIPR2 [20, 21]. This evidence concerns the gene VIPR2 and schizophrenia.