We surveyed variants in potential hereditary loci including those in TP53 (causative gene for Li–Fraumeni syndrome), BRCA2 (causative gene for hereditary breast/ovarian cancer), and mismatch repair genes (MSH2, MSH6, PMS2, and EPCAM, i.e., causative genes for Lynch syndrome), but found only common SNPs. This evidence concerns the gene PMS2 and Lynch syndrome.