In addition, immunohistochemistrical analysis of the proliferative maker Ki67 and the transferase-mediated deoxyuridine triphosphate-biotin nick end labeling (TUNEL) assay were performed in the tumor sections, and the results showed decreased cell proliferative rate and increased apoptosis in the mice treated with miR-150 oligonucleotides (Figure 3h). Here, MKI67 is linked to neoplasm.