Heritability of AAA is >0.7,4 and individuals with a first-degree relative with AAA have a 2-fold higher risk of developing an AAA.5 Genome-wide association studies (GWAS) have identified 3 AAA risk loci on chromosomes 9 (DAB2IP6 [DAB2 interacting protein]), 12 (LRP17 [low-density lipoprotein receptor related protein 1]), and 19 (LDLR8 [low-density lipoprotein receptor]). The gene discussed is LRP1; the disease is triple-A syndrome.