Both analyses revealed a central role for MMP9 in AAA, with IPA identifying direct interactions (physical contact between 2 molecules such as binding or phosphorylation) between ERG, IL6R and LDLR, and MMP9, and Consensus PathDB identifying a direct interaction between ERG and MMP9 with secondary interactions (interactions without physical contact, such as signaling events) between both SMYD2 and LDLR, and MMP9. This evidence concerns the gene SMYD2 and triple-A syndrome.