LDLR and triple-A syndrome: Both analyses revealed a central role for MMP9 in AAA, with IPA identifying direct interactions (physical contact between 2 molecules such as binding or phosphorylation) between ERG, IL6R and LDLR, and MMP9, and Consensus PathDB identifying a direct interaction between ERG and MMP9 with secondary interactions (interactions without physical contact, such as signaling events) between both SMYD2 and LDLR, and MMP9.