The long noncoding RNA ANRIL (CDKN2BAS1), our strongest hit in the genome (Figure 1), has been reported in numerous studies as a GWAS hotspot and a candidate gene for CAD, intracranial aneurysms, and diverse cardiometabolic disorders40; however, this was not represented in either the IPA or Consensus PathDB networks. This evidence concerns the gene CDKN2B-AS1 and Dilatation of the cerebral artery.