In addition, although the AAA association with rs599839 (1p13.3) showed strong long-range chromatin interaction with SORT1 (as previously reported specifically in AAA9), it also had predicted distal interactions with other genes including BCAR3 (breast cancer antiestrogen resistance 3; 1p22.1) and NOTCH2 (notch 2 member of type 1 transmembrane protein family; 1p12-p11). The gene discussed is NOTCH2; the disease is breast cancer.