In the screening phase, our data showed that plasma levels of inflammatory oxylipins, such as PGE2 and 12-HETE, oxidized PCs, and eDGs are increased in patients with SJS/TEN-associated chronic SOCs, whereas phosphoglycerolipids, such as LPCs, PCs, ePCs, and ePEs, are reduced. Here, CISH is linked to toxic epidermal necrolysis.