Because our present study has demonstrated decreased ePCs as the most specific plamsa lipid alterations in the chronic SOCs, further studies addressing ePC levels as well as outcomes of restoring ePCs in eye tissues of patients with the chronic SOCs would advance to understand the ePC-related pathophysiological mechanisms that are potential therapy targets for SJS/TEN-associated chronic SOCs. This evidence concerns the gene CISH and toxic epidermal necrolysis.