We analyzed the demographic characteristics and clinical profiles related to pregnancy such as patient mean age, body mass index, duration of infertility, basal FSH levels, basal LH levels, thickness of endometrium, number of oocytes retrieved, number of fertilized oocytes, number of cleavage embryos, number of transferred embryos and number of good quality embryos among different genotypes of TP53 codon 72 polymorphism and HDM2 SNP309 polymorphism (shown in Tables 3 and 4), and no significant difference was found. The gene discussed is TP53; the disease is Infertility.