Toll-like receptor 2 (TLR2) expression is induced in the CP during the acute phase of the LPS mouse model31 and genes related to IL-2, IL-4, IL-6 and IL-10 signaling were also increased in the CP of mice that received LPS once every 2 weeks for 3 months.74 We also found a substantial numbers of genes that were common to the co-expression modules of both the LPS mouse model (LPS_3h_M2) and the schizophrenia-associated immune/inflammation response module (S_Co_M16). This evidence concerns the gene TLR2 and schizophrenia.