We confirmed directionality of the T1D-associated DVPs (FDR<0.001), indicating robust technical detection across assay platforms in both CD14+ cells (P=7.7 × 10−5, one-tailed Fisher's exact test; Fig. 3d) and CD4+ cells (P=7.8 × 10−3; Fig. 3d). Here, CD4 is linked to type 1 diabetes mellitus.