Furthermore, to better understand the relationship of HTR1A and HTR5A with executive function under pathological and non-pathological conditions, our secondary purpose was to evaluate the relationship of the schizophrenia-associated variants in HTR1A and HTR5A with four WCST indices (perseverative errors, non-perseverative errors, total errors and trials to complete the first category) in SCZ patients and healthy individuals. The gene discussed is HTR1A; the disease is schizophrenia.