The top significant network consisted of 25 upregulated genes, which associate with protein synthesis, gene expression, and cancer (RPL13A, RPL41, RPL27A, RPLP0, RPL5, RPL11, RPL30, 60S ribosomal subunit, HSP90AA1, HSP, HSP90AB1, HSPA9, ENO1, 14-3-3, YWHAZ, RPS3, Tubulin, SAT1, GNB2L1, EIF4A, EIF4A1, TUBB, YWHAE, NOP56, PAPOLA) (Fig. 7b). Here, PAPOLA is linked to cancer.