VEGFB and neoplasm: It has been reported that MC density is increased at the margins of various tumors in humans [9, 10], modulating many aspects of the tumor natural history [11–13] and correlating with angiogenesis through the synthesis and release of a wide spectrum of angiogenic factors, such as Vascular Endothelial Growth Factor-A (VEGF-A) and Vascular Endothelial Growth Factor-B (VEGF-B), [14,15] and tumor invasion by releasing cytokines and proteases [12].