BCL2 and acute myeloid leukemia: To explore whether FTI-induced apoptosis could be mediated by decreased expression of anti-apoptotic Bcl-2 and Bcl-X(L) or increasing in proapoptotic Bcl-X(S) proteins, AML cells were exposed for 48 hours to FTIs or control medium and Bcl-2 or Bcl-X(L)/(S) were measured.