Various bile acids have been reported to have anti-neoplastic and anti-carcinogenic properties in a number of cancer cell models: chenodeoxycholic acid (CDCA) reduced growth of tamoxifen-resistant breast cancer cells by downregulation of human epidermal growth factor receptor 2 (HER2) promoter activity (Giordano et al., 2011), LCA and several of its synthetic enantiomers reduced colon cancer cell proliferation and viability (Katona et al., 2009). This evidence concerns the gene ERBB2 and malignant colon neoplasm.