In the temporal cortex, densitometric analyses revealed that the expression levels of TNFR1 and TNFR2 were significantly different between the AD and HPC groups (AD<HPC) and the AD and ND groups (AD<ND) (p<0.05; Kruskal–Wallis non-parametric analysis with Steel–Dwass post-testing). This evidence concerns the gene TNFRSF1B and Alzheimer disease.