Moreover, miRNA-146a is a target of MITF (Microphthalmia-associated Transcription Factor), a protooncogenic transcription factor acting as a master regulator of melanocyte development, function and survival; it also may be implicated in choroidal melanoma pigmentation and proliferation (Ozsolak et al., 2008; Chen et al., 2011; Yajima et al., 2011). This evidence concerns the gene MITF and choroidal melanoma.