We then investigated whether CIT-K was essential for cytokinesis in a panel of cell lines comprising both non-cancerous immortalized cell lines (hTERT-RPE1 and HB4a) and cancer cell lines from breast (CAL51 and MDA-MB-231), colorectal (HCT116 and VACO5) and cervical (HeLa Kyoto and ME180) origins (Table 1). This evidence concerns the gene CIT and cancer.