QRT-PCR results showed that miR-663b expression was significantly lower in pancreatic cancer tissues than that in adjacent normal pancreatic tissues from patients with pancreatic cancer (Figure 4A); while the mRNA expression level of IGF2 was significantly increased in pancreatic cancer tissues when compared to adjacent normal pancreatic tissues from patients with pancreatic cancer (Figure 4B). This evidence concerns the gene IGF2 and pancreatic neoplasm.