BSG and malignant colon neoplasm: While others have demonstrated the relationship between Ras and CD147 using the same model [96], this analysis revealed for the first time the upregulation of CD147 not only on the surface of the MCF10A-KRasG12Vmodel cell line but also on the surface of pancreatic, lung, and colon cancer cell lines expressing KRas mutants at the endogenous levels.