We evaluated the associations of hEXO1 SNPs with various clinicopathological features of HCC including: tumor size, tumor number, TNM staging (tumor-node-metastasis staging, a cancer staging notation system that describes the stage of a cancer which originates from a solid tumor with alphanumeric codes), combined with liver cirrhosis, AFP level, and tumor metastasis (Table 4∼9). This evidence concerns the gene AFP and cirrhosis of liver.