Knockdown of LSD1 in HPV16 E7-overexpressing cervical cancer cells also reduced the expression of Vimentin and increased the expression of E-cadherin compared to their expression in the HPV16 E7-overexpressing control group, resulting in levels similar to those in the blank group (Figure 3A), indicating that the enhancement of the EMT by HPV16 E7 was diminished by reduced LSD1 expression. The gene discussed is CDH1; the disease is cervical cancer.