The effects on endogenous antioxidant enzymes and GSH levels measured in homogenates of the cardiac tissues have been depicted in Fig 7.The levels of CAT, SOD, GPx, GST, G6PD and GSH were significantly (p < 0.05–0.01) decreased in the myocardial tissues of T2D rats as compared with normal animals. This evidence concerns the gene CAT and type 2 diabetes mellitus.