TNFRSF8 and mycosis fungoides: The heterogeneous group of CTCL includes indolent variants, following a chronic course with slow progression over years and decades (e.g. mycosis fungoides (MF) and the CD30+ lymphoproliferative disorders lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (C-ALCL)), and aggressive variants (e.g. Sezary syndrome (SS) and extranodal natural killer T-cell lymphoma, nasal type).[30,31]