Further Western blot analysis of EMT in lung cancer cell lines also demonstrated that H358 and H441 cells with lower endogenous FGFR and brachyury had higher E-cadherin and β-catenin expressions and lower Snail and fibronectin expressions than H226 and H460 cells with higher endogenous FGFR and brachyury (Figure 4B). The gene discussed is FN1; the disease is lung cancer.