While a basal perivascular and perilymphatic protein expression was detected in skin, liver, and colon biopsies from non-GvHD controls (Doni A., (IRCCS) - Humanitas Clinical and Research Center, Rozzano (MI), Italy, personal oral communication April 2016), PTX3 accumulation was evident in GvHD inflamed dermal and colon extracellular matrix. The gene discussed is PTX3; the disease is graft versus host disease.