However, when we compared PTX3 levels at GvHD onset with those measured in patients without GvHD, excluding plasma samples collected from patients suffering from clinically proven infections, we failed to notice significant differences from our previous analysis (data not shown), suggesting robustness of PTX3 as a biomarker for GvHD diagnosis at the onset of clinical symptoms. The gene discussed is PTX3; the disease is graft versus host disease.