The mouse version of FOXK1, Foxk1/MNF, exists as two isoforms, MNFa and MNFb, which differ through their alternative splicing leading to the production of the C-terminally truncated MNFb isoform.18, 19 The human FOXK1, the protein feature analysis predicted a forkhead domain, an FHA domain and a nuclear localization.16 Recently, we found that FOXK1 was overexpressed in 16 types of cancerous human tissues and appeared to have a crucial role in the development and progression of human carcinomas.20 The gene discussed is FOXK1; the disease is carcinoma.