Several studies in the recent past are in agreement with our findings as they have associated various Spliceosome complex genes including U2 Small Nuclear RNA Auxillary Factor 1 (U2AF2), pre-mRNA processing factor (PRPF), splicing factor 3 (SF3) subunits and Serine Arginine rich factors (SRSF) using whole exome/genome technologies in myelodysplastic syndromes and in other hematologic disorders42, 43, 44. The gene discussed is U2AF1; the disease is myelodysplastic syndrome.