TNF and coronary artery disorder: In line with this, fatty acid (FA)-induced expression of Tnfα, IL6, and Casp9 was significantly decreased in Cpt1bm−/− primary myotubes compared to Cpt1bfl/fl myotubes, indicating that the inflammatory response to fatty acids is reduced in muscle cells from CHD-fed Cpt1bm−/− mice (Fig. 1c).