Genomic analyses of 538 human HGSC and 580 lung squamous cell carcinoma in The Cancer Genomics Atlas (TCGA) and high-resolution single-nucleotide polymorphism-based copy-number databases (Affymatrix SNP6 and Nexus Copy Number program; Supplementary Fig. 1b) demonstrated the USP13 gene-containing amplicon across chromosome 3q26.2–3q26.3. Here, USP13 is linked to squamous cell lung carcinoma.