HTT and Huntington disease: Here, we used inducible PC12 cell model of HD, i.e., PC12 HD-Q23 and PC12 HD-Q74 cycling cells, to determine the effect of short-term expression of Htt and mHtt on the cell viability and mitochondria functioning in intact cells as well as properties of VDAC isolated from the cells differing in viability and mitochondrial coupling status.