Advance in medical research have led to the discovery of biomarkers for the diagnosis of AD pathologies, such as decreased cerebrospinal fluid (CSF) β-amyloid 1–42 (Aβ1-42), positive amyloid positron emission tomographic (PET) imaging and presence of the Apolipoprotein E ɛ4 allele (ApoE ɛ 4) for amyloid pathology [2–6]. This evidence concerns the gene APOE and Alzheimer disease.