Patients with NAFLD showed increased TNF-α than those with morbidly obese subjects but without NAFLD (mean 37.41 vs.31.41 pg/ml, P < 0.046). Serum levels of IL-10, in contrast, were decreased in NAFLD (mean 61.05 vs. 76.40 pg/ml, P < 0.002), which suggests an imbalance between the pro-inflammatory and anti-inflammatory cytokines. The gene discussed is IL10; the disease is metabolic dysfunction-associated steatotic liver disease.