ALDH1A1 and neoplasm: Patient 127 had a histology of papillary serous adenocarcinoma and, as previously described in Dobbin et al, the histology of the tumor was maintained for 6 generations and a significant increase in the CSC markers ALDH1A1 and CD133 were seen in the PDX treated with carboplatin and paclitaxel for 4 weeks [24].