Thorenoor et al recently profiled expression of disease-associated lncRNAs in CRC tumor tissues and identified ZFAS1 (zinc finger antisense 1), previously known to be a tumor suppressor gene in human breast cancer [14, 15] and oncogene in hepatocellular carcinoma [16], to be overexpressed in CRC tissue. Here, ZFAS1 is linked to colorectal carcinoma.