Promotes cellular proliferation, migration, and invasion via 1) binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex 2) increasing expression of AKAP-9 via promoting SRPK1-catalyzed SRSF1 phosphorylation in colorectal cancer cells. The gene discussed is SRSF1; the disease is colorectal cancer.