EGFR and colorectal cancer: Hierarchical analysis showed that EGFR expression mainly affects the PFS of TNM stage I-II colorectal cancer patients, the median PFS was 33.53 months in the TNM stage I-II colorectal cancer patients with high EGFR expression patients, The median PFS was 70.43 months in the TNM stage I-II colorectal cancer patients with low EGFR expression (χ2=9.530, P=0.002); The median PFS was 19.2 months in the TNM stage III-IV colorectal cancer patients with high expression EGFR, the PFS of the TNM stage III-IV colorectal cancer patients with low EGFR expression was 37.87 months (χ2=7.97, P=0.005).