The incidence of hypoglycaemia observed in the present study is less than that previously reported in studies involving European children; the previously mentioned study by Schoberet al.reported a greater proportion of patients experiencing ≥1 episode of symptomatic hypoglycaemia (78.9% and 79.3%, versus 69.2% and 75.9% in the present study) and severe hypoglycaemia (23.0% and 28.6%, versus 0.9% and 1.9% in the present study) with both insulin glargine and NPH insulin [11]. The gene discussed is INS; the disease is Hypoglycemia.