These results [44–48] imply that under normal physiological condition there is a balance maintained between pro- and anti-inflammatory bioactive lipids (LTB4 vs LXA4/resolvins/protectins/maresins) to limit inflammation, regulate production of various cytokines, control bacterial proliferation and their ability to produce inflammation and ultimately control, prevent and help in the recovery from sepsis and ARDS as proposed previously [49, 50]. The gene discussed is CD59; the disease is acute respiratory distress syndrome.