RPS6KA2 and inflammatory bowel disease: The RPS6KA2/VMP1 probes (cg17501210/cg12054453) and RPS6KA2/TNFSF10 probes (cg17501210/ cg01059398) were able to accurately discriminate between disease and control in CD (area under receiver operating characteristic curve (AUC)=0.84/0.81 respectively); IBD (AUC=0.79/0.79) and UC (AUC=0.73/0.71; Supplementary Fig. 11A–C).