SDHB and paraganglioma: Interestingly, SDH-deficient pheochromocytomas and paragangliomas,11Sdhb-deficient cells,7 and IDH-mutant cells also exhibit EMT.12 Our results indicate that, at least in Sdhb-deficient cells, EMT induction is mediated by epigenetic suppression of miR-200, similar to that observed in FH-deficient cells.