TNF and neoplasm: These tumor-associated dendritic cells were transformed from immunosuppressive to highly immunostimulatory cells, capable to trigger a potent antitumor immune response by the administration of miR-155 mimetics, which inhibited CEBP/β, SOCS1, PU.1 transcription factors, leading to upregulation of TNF-α, IL-12 and IFN-γ in the tumor microenvironment [185].