Kynurenine aminotransferase 1 is known to be involved in tryptophan metabolism (DBGET: T01001, hsa00380), where it converts kynurenine, an intermediate of the tryptophan degradation pathway, into kynurenic acid [17], a neurotoxic compound associated with schizophrenia [18]. The gene discussed is KYAT1; the disease is schizophrenia.