IGHE and Renal atrophy: Pre-treatment eGFR and serum IgE level were significant risk factors for development of renal atrophy 24 months after the start of therapy with an odds ratio (OR) of 0.520 (per 10 mL/min/1.73 m2, 95% CI 0.273–0.993, P = 0.048) and 1.090 (per 10 IU/mL, 95% CI 1.013–1.174, P = 0.022), respectively, in age-adjusted, sex-adjusted, serum IgG4 level-adjusted logistic regression analysis (Table 3).