S2-25:J-03 belongs to type 1 junction (virus-human-human), with the left element from HPV16 E1 gene (122 bp), middle element from chromosome 9 (261 bp) overlapped with suppressor of cancer cell invasion (SCAI) gene and the right element from chromosome 4 (159 bp) overlapping with Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) gene. This evidence concerns the gene SCAI and cancer.