In ovaries of mammals, FSHR interacts with its ligand follicle-stimulating hormone (FSH) and has a crucial role in follicular development, steroidogenesis, and female infertility.1, 2, 3, 4 In pigs, Sato et al.5, 6 detected a quantitative trait loci (QTL) for the number of corpora lutea on SSC3 with genome-wide significance in an F2 resource population by crossing a Duroc boar with a Meishan sow, and further identified FSHR as a functional gene for this QTL by fine mapping, association, and mutational analyses. This evidence concerns the gene FSHR and female infertility.