Our PCR array data showed that both M1-related genes (Ccl2, Ccl3, Ccl4, Ccl5, Il12b, Il1b and Ccl1) and M2-related genes (Il10, Tgfb2 and Il1rn) were significantly upregulated in NM11-shsST2 tumours compared with NM11-shCont tumours (Fig. 7f). The gene discussed is IL1RN; the disease is neoplasm.