IL1RN and neoplasm: Consistent with this report, our PCR array analysis revealed a significant upregulation of both M1-related genes (Ccl2, Ccl3, Ccl4, Ccl5, Il12b, Il1b and Ccl1) and M2-related genes (Il10, Tgfb2 and Il1rn) in sST2 low-expressing tumours.