CCL7 and neoplasm: In support of this result, expression of the Ccl7 (Chemokine (C-C Motif) Ligand 7) gene, which encodes monocyte chemotactic protein 3 produced by macrophages that strongly attracts monocytes during inflammation and metastasis35, 36, was significantly upregulated in NM11-shsST2 and LuM1-VC tumours compared with NM11-shCont and LuM1-sST2 tumours (Fig. 7e).